Table 5.
Basic analysis of association between sex and the risk of gastric cancer
| SNP | Allele (Aa/B) | Male | Female | ||||||
|---|---|---|---|---|---|---|---|---|---|
| MAF (case) | MAF (control) | OR (95% CI) | p value | MAF (case) | MAF (control) | OR (95% CI) | p value | ||
| rs2274976 | G/A | 0.053 | 0.056 | 0.94 (0.64−1.38) | 0.758 | 0.081 | 0.082 | 0.98 (0.59−1.64) | 0.950 |
| rs1801133 | T/C | 0.462 | 0.440 | 1.09 (0.92−1.30) | 0.314 | 0.526 | 0.472 | 1.24 (0.94−1.64) | 0.131 |
| rs1805087 | G/A | 0.070 | 0.102 | 0.66 (0.48−0.91) | 0.010* | 0.114 | 0.096 | 1.21 (0.77−1.91) | 0.413 |
| rs2853522 | A/C | 0.422 | 0.419 | 1.01 (0.85−1.21) | 0.885 | 0.448 | 0.424 | 1.10 (0.83−1.46) | 0.503 |
| rs1801394 | G/A | 0.279 | 0.301 | 0.90 (0.74−1.09) | 0.281 | 0.227 | 0.252 | 0.87 (0.63−1.22) | 0.423 |
| rs1532268 | T/C | 0.159 | 0.127 | 1.31 (1.02−1.68) | 0.036* | 0.133 | 0.130 | 1.03 (0.68−1.56) | 0.887 |
| rs162036 | G/A | 0.163 | 0.167 | 0.97 (0.77−1.22) | 0.787 | 0.162 | 0.186 | 0.85 (0.58−1.23) | 0.385 |
Value of HWE‐p ≤ 0.05 was excluded. Value of p was adjusted by age.
SNP: single nucleotide polymorphism; MAF: minor allele frequency; ORs: odds ratios; 95% CI: 95% confidence interval.
a
Minor allele.
*
Value of p ≤ 0.05 indicates statistical significance.