Table 2.
d‐glucose | d‐galactose | Glucose versus galactose | |||||||
---|---|---|---|---|---|---|---|---|---|
Tissue | K m ± SEM (mmol/L) | V max ± SEM (μA/cm2) | Hill slope | Tissue | K m ± SEM (mmol/L) | V max ± SEM (μA/cm2) | Hill slope | K m | V max |
Jejunum | 4.6 ± 0.4A | 11.1 ± 2.3A | 4.3 ± 0.5 | Jejunum | 19.1 ± 1.2A | 30.0 ± 5.0A | 11.5 ± 1.8 | * | * |
Ileum | 6.3 ± 0.9A | 100.7 ± 9.3B | 3.1 ± 0.6 | Ileum | 17.4 ± 2.1A | 60.3 ± 7.1B | 2.7 ± 0.9 | * | * |
Distal Colon | nd | nd | nd | Distal colon | nd | nd | nd | nd | nd |
V max (μA) and K m (mmol/L) represent sodium‐dependent electrogenic d‐glucose and d‐galactose absorption for each tissue type in pig. ND represents nondetectable transport of those substrates. The area of intestinal segment was 1 cm2. Data are presented as means ± SEM. The same letter superscripts for K m values between the jejunum and ileum in response to d‐glucose and d‐galactose transport indicates no significant differences. Different letter superscripts for the V max values between the jejunum and ileum in response to d‐glucose and d‐galactose transport represents significance (Student's t‐test, P < 0.05). Single asterisk represents significant difference between jejunal K m and V max values for d‐glucose and d‐galactose transport (Student's t‐test, P < 0.05). Single asterisk represents significant difference between ileal K m and V max values for d‐glucose and d‐galactose transport (Student's t‐test, P < 0.05).