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. 2019 Apr 30;13:402. doi: 10.3389/fnins.2019.00402

Table 5.

Active sensory training study characteristics.

Author, year Study design Sample size Age (years) Gender (M:F) Stroke duration (time since stroke) mean (SD) Side of stroke (affected side) Intervention Target duration Control condition Outcome measures Direction of effects (+ positive, – negative, +/- both)
Byl et al., 2003 RCT (Crossover) 8E, 10C 69.0, 58.5 5:3, 7:3 4.5, 4.8 5:3, 5:5 Sensory discrimination training (and mental imagery, mirror and functional practice at home) UL
1.5 h/week for 4 weeks,
4 sessions
[and HEP CIMT 7 h + 15–90 min functional practice]
Sensory discrimination (kinesthesia, graphesthesia, stereognosis), PPT, WMFT, Cal-FCP, UL/LL strength and ROM, gait speed +
Carey et al., 2011 RCT (Parallel/Crossover) 25E, 25C 61.08 ± 14.38E, 60.96 ± 11.17C 17:8E, 20:5C 32.57 (12.22–111.22)E, 51.86 (20.57–72.53)C (weeks) 40:60%E, 44:56%C Somatosensory discrimination training (texture discrimination, limb position sense, and tactile object recognition) UL
60 min, 3 sessions/week for ~4 weeks,
10 sessions
Exposure to sensory stimuli Composite index of functional somatosensory discrimination capacity: FMT, WPST, fTORT +
Chanubol et al., 2012 RCT (Parallel Group) 20E, 20C 63.2 ± 10.1 9:11E, 11:9C - 1:19E, 1:19C Perfetti's method (cognitive sensory motor training therapy- perception tasks: sensing and discriminating limb positions) UL
30 min, 5 times/week for 4 weeks,
20 sessions
Standard OT ARAT, BI, BBT
de Diego et al., 2013 RCT (Parallel Group) 12E, 9C 61.9 ± 9.7E, 60.6 ± 15.6C - 44.7 ± 24.5E, 60.7 ± 58.2C (months) Sensory stimulation and functional activity training (targeting tactile stimulation, mental imagery and practice of ADL's at home) UL
1 h, 2 days/week over 8 weeks,
16 sessions
[and HEP 30 min/day over 8 weeks total 28 h]
Standard rehabilitation FMA-UE, MAL, SIS-16, sensory discrimination battery: tactile sensibility (monofilaments), proprioceptive sensibility (passive ROM), consistency and weight discrimination (ordering consistency and weight of objects) +
Lynch et al., 2007 RCT (Parallel Group) 10E, 11C 61.0 ± 15.8, (21–77)E, 62.0 ± 12.3, (38–82)C 7:3E, 9:2C 48.7 ± 31.1 (19–122)E, 47.8 ± 27.7 (13–112)C (days) 5:5E, 8:3C Sensory retraining (education, detection, localization, discrimination and proprioception) LL(foot)
30 min, 10 sessions over
2 weeks
Sham relaxation and standard PT LT monofilaments, distal proprioception test, BBS, gait time and Iowa +/–
Morioka and Yagi, 2003 RCT (Parallel Group) 12E, 14C 62.6 ± 13.3 (51–79)E, 61.3 ± 11.0 (56–73)C 9:3E, 8:6C 65.4 ± 18.6 (36–106)E, 61.9 ± 20.8 (31–111)C (days) 6:6E, 5:9C Perceptual learning exercises (hardness discrimination) LL
10 trials/session, 10 days over
2 weeks
Standard PT/OT (no perceptual learning exercise) SBT (postural sway) +/–

Abbreviations: –, not known; UL/LL, upper and lower limb; Outcome measures: Cal-FCP, California Functional Capacity Evaluations; FMT, Fabric Matching Test; fTORT, Tactile Object Recognition Test; PPT, Purdue Pegboard Test; SBT, Stabilometer Balance Test; WMFT, Wolf Motor Function Test; WPST, Wrist Position Sense Test; Interventions: ADL's, activities of daily living; CIMT, constraint induced movement therapy; HEP, home exercise program.