Table 2.
Clinical-pathologic features of the series.
| Variable | N | % | |
|---|---|---|---|
| Gender | Male | 115 | 63.2 |
| Female | 67 | 36.8 | |
| Behavioral risk factors | None | 67 | 36.8 |
| Alcohol | 11 | 6 | |
| Smoke | 55 | 30.2 | |
| Smoke and alcohol | 43 | 23.6 | |
| Pack/Year | < or = 10 | 65 | 35.7 |
| >10 | 70 | 38.5 | |
| Not available | 47 | 25.8 | |
| Subsite | Tongue | 90 | 49.5 |
| Oral floor | 46 | 25.3 | |
| Retromolar trigone | 18 | 9.9 | |
| Alveolar crest | 18 | 9.9 | |
| Cheek mucosa | 7 | 3.8 | |
| Hard palate | 2 | 1.1 | |
| Lips | 1 | 0.5 | |
| Treatment | Surgery | 78 | 42.9 |
| Surgery+RT | 61 | 33.5 | |
| Surgery+RT+CHT | 43 | 23.6 | |
| pT | T1 | 36 | 19.8 |
| T2 | 55 | 30.2 | |
| T3 | 6 | 3.3 | |
| T4 | 85 | 46.7 | |
| pN | N0 | 97 | 53.3 |
| N1 | 29 | 15.9 | |
| N2a | 2 | 1.1 | |
| N2b | 42 | 23.1 | |
| N2c | 12 | 6.6 | |
| N3 | 0 | 0 | |
| ENE | Absent | 43 | 50.6 |
| Present | 42 | 49.4 | |
| AJCC stage | I | 23 | 12.6 |
| II | 39 | 21.4 | |
| III | 16 | 8.8 | |
| IV | 104 | 57.1 | |
| Surgical margins | Negative | 97 | 53.3 |
| Close (< 5 mm) | 53 | 29.1 | |
| Positive | 32 | 17.6 | |
| Grading | 1 | 18 | 9.9 |
| 2 | 87 | 47.8 | |
| 3 | 77 | 42.3 | |
| Perineural spread | Absent | 92 | 50.5 |
| Present | 90 | 49.5 | |
| Lymphovascular invasion | Absent | 131 | 72 |
| Present | 51 | 28 | |
| Bone invasion | Absent | 149 | 81.9 |
| Cortical | 15 | 8.2 | |
| Medullary | 18 | 9.9 | |
CHT, chemotherapy; ENE, extranodal extension; RT, radiotherapy.