Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Key Receptor-Ligand Interactions That Turn OFF the T Cell
Oncolytic viruses induce immune responses that, upon infecting tumor cells, induce apoptosis or express the transgenes that, when presented or released by tumor cells, attract immune cells. The transgenes could be (1) key epitopes that attract immune cells, (2) immune-stimulatory blockers of immune checkpoints, or (3) key genes from non-human species that have anti-tumor effects.
