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. 2019 Apr 30;10:393. doi: 10.3389/fgene.2019.00393

Table 1.

Types of cancer with the highest occurrence of chromothripsis.

References Cancer type Cases with chromothripsis/ total number of cases Chromothripsis frequency
Rausch et al., 2012 SHH medulloblastoma with mut TP53 10/10 100%
Rausch et al., 2012 SHH medulloblastoma with wt TP53 0/22 0%
Northcott et al., 2012; Rausch et al., 2012 Medulloblastoma, all subgroups 13/98; 139/1087 13%
Li et al., 2014 Acute lymphoblastic leukaemia with iAMP21 8/9 89%
Morrison et al., 2014 Invasive bladder carcinoma 81/150 60%
Zemanova et al., 2014 Myelodysplastic syndrome with CCR 77/157 49%
Rausch et al., 2012 Acute myeloid leukaemia with mut TP53 8/17 47%
Rausch et al., 2012 Acute myeloid leukaemia with wt TP53 1/91 1%
Przybytkowski et al., 2014 High-risk breast cancer 12/29 41%
Malhotra et al., 2013 Grade IV glioma (glioblastoma) 7/18 39%
Cohen et al., 2015 Grade IV glioma with mut IDH 9/24 37%
Cohen et al., 2015 Grade II–III glioma 5/45 11%
Malhotra et al., 2013 Lung adenocarcinoma 2/6 33%
Stephens et al., 2011 Osteosarcoma 3/9 33%
Nones et al., 2014 Esophageal adenocarcinoma 40/123 32%

iAMP, amplification of a chromosome 21 region; IDH, isocitrate dehydrogenase; SHH, Sonic Hedgehog.