Table 1.
References | Cancer type | Cases with chromothripsis/ total number of cases | Chromothripsis frequency |
---|---|---|---|
Rausch et al., 2012 | SHH medulloblastoma with mut TP53 | 10/10 | 100% |
Rausch et al., 2012 | SHH medulloblastoma with wt TP53 | 0/22 | 0% |
Northcott et al., 2012; Rausch et al., 2012 | Medulloblastoma, all subgroups | 13/98; 139/1087 | 13% |
Li et al., 2014 | Acute lymphoblastic leukaemia with iAMP21 | 8/9 | 89% |
Morrison et al., 2014 | Invasive bladder carcinoma | 81/150 | 60% |
Zemanova et al., 2014 | Myelodysplastic syndrome with CCR | 77/157 | 49% |
Rausch et al., 2012 | Acute myeloid leukaemia with mut TP53 | 8/17 | 47% |
Rausch et al., 2012 | Acute myeloid leukaemia with wt TP53 | 1/91 | 1% |
Przybytkowski et al., 2014 | High-risk breast cancer | 12/29 | 41% |
Malhotra et al., 2013 | Grade IV glioma (glioblastoma) | 7/18 | 39% |
Cohen et al., 2015 | Grade IV glioma with mut IDH | 9/24 | 37% |
Cohen et al., 2015 | Grade II–III glioma | 5/45 | 11% |
Malhotra et al., 2013 | Lung adenocarcinoma | 2/6 | 33% |
Stephens et al., 2011 | Osteosarcoma | 3/9 | 33% |
Nones et al., 2014 | Esophageal adenocarcinoma | 40/123 | 32% |
iAMP, amplification of a chromosome 21 region; IDH, isocitrate dehydrogenase; SHH, Sonic Hedgehog.