Fig. 7.

Exploration of parameters space of connections with the greatest effect on beta enhancement. Plot A. shows the impact of changing the coupling strength of MP-SP and REL-DP on the beta spectral output, when the coupling between REL-RET is weak. Here, although an increase in synaptic strength from MP-SP is enough to generate relatively high levels of beta spectral output, the connection from REL-DP seems to have a modulatory effect, i.e., the weaker the extrinsic coupling between relay and deep pyramidal cells the higher the beta spectral output. Plot B. considers a (constantly) strong coupling between REL-RET with the same changes in coupling strength between MP-SP and REL-DP. This time, we observe that an increase in beta is achieved with a concurrent strengthening of both MP-SP and REL-DP connections. In both plots, axis x and y denote a reduced connectivity strength when values are between −1 and 0 and an increased connectivity strength when values are between 0 and 1 for connections from middle pyramidal cells to superficial pyramidal cells and from relay cells to deep pyramidal cells respectively. Axis Z and colormap depict the magnitude of beta power.