Table 4.

Selected evaluation of cell nuclei (MPM versus conventional HP (H&E); mean grading system (0 [not visible], 1 [suggested without details], 2 [recognizable without further details], 3 [recognizable including all details]). Significantly better rating marked in bold and italics

	MPM	H&E	P
Cell nuclei [mean, 95-%-CI]
Liver	0.97 [0.73–1.22]	2.87 [2.76–2.98]	<0.001
Lung	0.76 [0.56–0.97]	2.42 [2.21–2.63]	<0.001
Heart	0.68 [0.45–0.92]	2.71 [2.54–2.88]	<0.001
Kidney	1.05 [0.81–1.29]	2.74 [2.59–2.88]	<0.001
Adrenal gland	0.84 [0.65–1.04]	2.53 [2.31–2.74]	<0.001
Testicle	0.95 [0.71–1.19]	2.30 [2.14–2.65]	<0.001
Neuroblastoma	0.45 [0.21–0.69]	1.87 [1.56–2.18]	<0.001
Rhabdomyosarcoma	0.74 [0.47–1.01]	2.40 [2.19–2.61]	<0.001

Note: Bold values indicate H&E was statistically significantly superior to MPM for the evaluation of cell nuclei in all normal tissues and tumor tissues. 

Abbreviation: n.s., non-significant; MPM, multiphoton microscopy; H&E, hematoxylin-eosin.