Table 3.
Distribution of IGF-1 rs6214 and (CA) 19 gene polymorphisms in studied groups
| Gene polymorphism | Patients (n=40) n (%) |
Controls (n=20) n (%) |
χ2 | p-value |
|---|---|---|---|---|
| IGF-1 (rs6214) gene polymorphism | ||||
| TT CT CC |
18 (45.0) 18 (45.0) 4 (10.0) |
4 (20.0) 7 (35.0) 9 (45.0) |
10.13 | 0.006* |
| Alleles T C |
(n=80) 54 (67.5) 26 (32.5) |
(n=40) 15 (37.5) 25 (62.5) |
9.82 | 0.002* |
| IGF-1 (CA) 19 gene polymorphism | ||||
| <192 192/194 >194 |
22 (55.0) 10 (25.0) 8 (20.0) |
8 (40.0) 1 (5.0) 11 (55.0) |
8.67 | 0.013* |
| Alleles 192 194 |
(n=80) | (n=40) | 6.90 | 0.009* |
| 54 (67.5) 26 (32.5) |
17 (42.5) 23 (57.5 |
|||
Note: *Statistically significant; χ2, Chi-square test.