Table 4.

Relation between IGF-1 rs6214 gene polymorphism and studied data in ST patients

		IGF-1 (rs6214) gene polymorphism in patients					Test of significance	p-value
TT (n=18)		CT (n=18)	CC (n=4)
		Demographic data
Age (years): mean ± SD		31.91±7.23		34.28±7.36	37.23±7.42		F=2.18	0.123
Sex: n (%)
Males		14 (77.8)		16 (88.9)	1 (25.0)		χ2=7.66	0.022*
Females		4 (22.2)		2 (11.1)	3 (75.0)
BMI: mean ± SD		31.33±6.27		33.18±5.56	28.51±4.32		F=2.98	0.059
								CT vs CC=0.054
		Clinical data
Site of lesion: n (%) Head and neck		11 (61.1)		10 (55.6)	4 (100.0)		χ2=2.79	0.248
Others		7 (38.9)		8 (44.4)	0
Number of lesions: Mean ± SD		9.17±3.94		9.56±5.31	3.00±0.82		K=10.68	0.005*
								CT vs CC= 0.053
								CC vs TT= 0.036
Duration of disease (years): mean ± SD		3.69±3.01		3.78±2.78	2.50±1.29		K=0.55	0.761
Acanthosis: n (%) Present		5 (27.8)		6 (33.3)	1 (25.0)		χ2=0.19	0.912
Absent		13 (72.2)		12 (66.7)	3 (75.0)
		Immunohistochemical results
Epidermis:
Intensity: n (%)
Mild	3 (16.7)		5 (27.8)			4 (100.0)	12.19	0.016*
Moderate	12 (66.7)		8 (44.4)			0
Strong	3 (16.7)		5 (27.8)			0
Dermal cells:
Endothelial cells: n (%) Mild Moderate Strong		4 (22.2) 5 (27.8) 4 (22.2)	5 (27.8) 2 (11.1) 7 (38.9)			3 (75.0) 0 (0.0) 1 (25.0)	5.24 8.07-	0.07 0.09
Stromal cells: n (%) Mild Moderate Strong Inflammatory cells: n (%) Mild Moderate strong		0 (0.0) 2 (11.1) 4 (22.2) 0 (0.0) 0 (0.0) 3(16.7)	0 (0.0) 1 (5.6) 6 (33.3) 0 (0.0) 0(0.0) 6(33.3)			1 (25.0) 0 (0.0) 1 (25.0)-		-

Note: χ², Chi-square test; *statistically significant.

Abbreviations: K, Kruskal–Wallis test; BMI, Body mass index; F, ANOVA test.