Fig. 5.
DWK-1 inhibition of ZIKV replication in primary human retinal endothelial cells. DWK-1 inhibition of ZIKV transcription in primary human retinal endothelial cells by qRT-PCR. ZIKV RNA accumulation in primary human retinal endothelial cells cultured under different conditions: 1. mock, 2. control morpholino, 3. DWK-1, 4. ZIKV, 5. control morpholino pretreatment and ZIKV, 6. DWK-1 pretreatment and ZIKV. Relative expression of intracellular ZIKV RNA was normalized to GAPDH mRNA. Values represent mean ± SD of 3 independent samples. *P < 0.001. ND, not detected.