Table 3.
Composition and characterization of ACZ-NV nanogels
CS concentration (%w/w) |
Viscosity (minimum) (cP) | Farrow’s constant (N) | Surface area of hysteresis loop | Time of adhesion (min) |
---|---|---|---|---|
0.8 | 89,352 | 1.4 | 3198.50 | 160 |
1.5 | 118,246 | 1.19 | 3983.95 | 290 |
2.5 | 110,832 | 1.12 | 3854.32 | 282 |
Note: *All of the gels were loaded with 1% w/w ACZ-NV selected formulation number 5 (F5).
Abbreviations: ACZ-NV, acetazolamide loaded nanovesicle; CS, chitosan.