Table 2.
Associations between LINC00673 variants and GC susceptibility
| SNP | Comparison | Cases (n=1392) | Controls (n=1364) | OR (95% CI) a | P-value |
|---|---|---|---|---|---|
| rs11655237 | GG | 775 | 838 | 1.00 (Reference) | |
| AG | 522 | 458 | 1.29 (1.07–1.54) | 0.006 | |
| AA | 95 | 68 | 1.58 (1.13–2.22) | 0.008 | |
| A vs G | 1.29 (1.12–1.48) | 4.1×10−4 | |||
| rs6501551 | AA | 1035 | 1023 | 1.00 (Reference) | |
| AG | 319 | 306 | 1.07 (0.72–1.59) | 0.731 | |
| GG | 38 | 35 | 1.15 (0.61–2.13) | 0.756 | |
| G vs A | 1.08 (0.81–1.45) | 0.649 | |||
| rs857510 | GG | 942 | 922 | 1.00 (Reference) | |
| AG | 415 | 404 | 1.05 (0.29–3.81) | 0.946 | |
| AA | 35 | 38 | 0.96 (0.78–1.19) | 0.738 | |
| A vs G | 1.03 (0.61–1.74) | 0.906 | |||
| rs9914618 | GG | 928 | 960 | 1.00 (Reference) | |
| AG | 414 | 363 | 1.23 (1.01–1.49) | 0.042 | |
| AA | 51 | 41 | 1.34 (0.84–2.13) | 0.217 | |
| A vs G | 1.21 (1.03–1.43) | 0.023 |
Notes: aAdjusted for age, gender, BMI, WHR, family history of cancer, drinking status, and HP infection. Bold values indicate statistically significant.
Abbreviations: BMI, body mass index; GC, gastric cancer; HP, Helicobacter pylori; WHR, waist-hip-ratio.