Fig. 1.
Characteristics of U87 and hG008 cells. a and f In vitro growth of U87 cells (a) and hG008 cells (f) expressing ffLuc. Scale bar, 100 μm. b–e and g–j 1 × 105 U87 cells or hG008 cells were implanted into the striatum of mouse brain. Representative H&E staining (b and g) and fluorescence images (c and h) of brain sections at 21 days (b and c) and 45 days (g and h) after implantation. Scale bar, 100 μm. d and i Kaplan-Meier plots showing survival of mice implanted with U87 cells (n = 9) (d) and hG008 cells (n = 8) (i). e and j Representative whole brain pictures and BLI images at 21 days and 56 days after implantation of U87 cells (e) and hG008 cells (j), respectively. Colored scale bars in (e) and (j) represent BLI radiance intensity in photons/second/cm2/steradian and photons/minute/cm2/steradian, respectively