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. 2019 May 6;20:229. doi: 10.1186/s12859-019-2829-y

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© The Author(s) 2019

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Illustration of Method. Displayed are the results for the gene MCM2 when our algorithm was applied to Ovarian Cancer Study GSE14764. a shows − log10(p_Sphere) vs the Neighborhood Radius. b shows − log10(p_Decay) vs the Neighborhood Radius. c shows − log10(p_Combined) vs the Neighborhood Radius. d shows the Number of Assayed Genes vs the Neighborhood Radius. In the top three plots, the dashed and dotted lines correspond to a significance level of 0.05 and 0.01 respectively. In the bottom plot, the solid line corresponds to the total number of genes assayed and on the network