Table 2.
“Disruptive” disease genes in high-grade ovarian cancer consistently found by GeneSurrounder
| −log10pGS | |||
|---|---|---|---|
| Gene | GSE14764 | GSE17260 | GSE9891 |
| ADRB3 | 3.033 | 2.933 | 3.554 |
| AURKA | 2.865 | 3.383 | 3.716 |
| CDC45 | 4.270 | 3.741 | 4.830 |
| CDC7 | 4.386 | 3.769 | 4.830 |
| DBF4 | 4.270 | 3.769 | 4.830 |
| IL7 | 3.055 | 2.898 | 2.910 |
| ITGAM | 2.961 | 3.024 | 3.094 |
| MCM2 | 4.830 | 3.372 | 4.830 |
| MCM3 | 4.830 | 3.383 | 4.830 |
| MCM4 | 4.830 | 3.394 | 4.830 |
| MCM5 | 4.830 | 3.372 | 4.830 |
| MCM6 | 4.830 | 3.428 | 4.830 |
| ORC4 | 4.386 | 3.172 | 4.830 |
| ORC6 | 4.386 | 3.691 | 4.830 |
| TTK | 2.904 | 3.089 | 4.830 |
At a threshold of p=0.05 and with a diameter of D=34, the Bonferroni corrected threshold is −log10(p)≥2.83. Listed are the genes that pass this threshold in all three studies