Fig. 2.

Change from baseline in systolic blood pressure (SBP) by baseline SBP and antihypertensive therapy use. Change from baseline in SBP at Week 26 by baseline SBP level (a) and baseline antihypertensive therapy, diuretics, and renin–angiotensin–aldosterone system (RAAS) blocker use (b). CI confidence interval; LS least squares. *Placebo-adjusted difference in LS mean (95% CI). ^†Mean baseline SBP across groups was 126–127 or 132–133 mmHg in patients with or without baseline antihypertensive therapy, respectively