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. 2019 Apr 23;12:1279–1286. doi: 10.2147/JPR.S190646

Table 2.

Variables associated with moderate-to-good pain relief, 2 weeks after ESI

Variable Number of patients (%) Odds ratio (95% CI) P-value
Demographic variables
Age at first intervention, years
≤60 4/9 (44) Reference
>60 20/33 (61) 1.86 (0.42–8.21) 0.38
Sex
Male 14/23 (61) Reference
Female 10/19 (53) 0.72 (0.21–2.47) 0.60
Diabetes mellitus
No 19/37 (51) Reference
Yes 5/5 (100) 10.44 (0.41–265.7) 0.15
Inflammatory disease
No 17/30 (57) Reference
Yes 7/12 (58) 1.05 (0.27–4.07) 0.94
Malignant disease
No 20/34 (59) Reference
Yes 4/8 (50) 0.71 (0.15–3.32) 0.66
Concurrent medicationsa
Aspirin
No 23/39 (59) Reference
Yes 1/3 (33) 0.42 (0.04–4.75) 0.48
Acetaminophen
No 23/40 (58) Reference
Yes 1/2 (50) 0.75 (0.04–12.77) 0.83
Gabapentin
No 10/18 (56) Reference
Yes 14/24 (58) 1.12 (0.33–3.84) 0.86
Local anesthetic
No 21/37 (57) Reference
Yes 3/5 (60) 1.07 (0.16–7.13) 0.94
Opioid
No 19/29 (66) Reference
Yes 5/13 (38) 0.35 (0.09–1.34) 0.12
SSRI or SNRI
No 24/40 (60) Reference
Yes 0/2 (0) 0.14 (0–5.86) 0.29
Steroid
No 24/41 (59) Reference
Yes 0/1 (0) 0.23 (0–23.01) 0.53
Tricyclic antidepressant
No 20/36 (56) Reference
Yes 4/6 (67) 1.45 (0.24–8.72) 0.68
Symptoms and interventions
Level of ESI
Thoracal 19/29 (66) Reference
Cervical 1/2 (50) 0.54 (0.03–9.54) 0.76
Lumbar 4/7 (57) 0.69 (0.13–3.7) 0.95
ESI medication
Steroid only 11/15 (73) Reference
 Steroid + local anesthetic 13/22 (59) 0.56 (0.14–2.28) 0.41
Approach of ESI
Interlaminar 23/37 (62) Reference
Transforaminal 1/1 (100) 1.87 (0.02–184.23) 0.78
Location of cutaneous rash
Thoracic 21/34 (62) Reference
Cervical 1/1 (100) 1.89 (0.01–183.7) 0.58
Extremity 1/2 (50) 0.63 (0.04–10.93) 0.92
Lumbar 1/5 (20) 0.21 (0.03–1.78) 0.23

Note: aNo patients concurrently used nonsteroidal anti-inflammatory drugs.

Abbreviations: ESI, epidural steroid injection; SNRI, serotonin–norepinephrine reuptake inhibitor; SSRI, selective serotonin reuptake inhibitor.