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. 2019 May 3;2(5):e193433. doi: 10.1001/jamanetworkopen.2019.3433

Figure 3. Correlation of Treatment Effects on Overall Survival (OS) Hazard Ratio (HR) With the Ratios of OS and Progression-Free Survival (PFS) Milestone Restricted Mean Survival Times (RMSTs).

Figure 3.

A, Correlation of treatment effects on OS HR with the ratio of 6-month PFS milestone RMST. B, Correlation of OS HR with the ratio of 9-month PFS milestone RMST. C, Correlation of treatment effects on OS HR with the ratio of 9-month OS milestone RMST. D, Correlation of treatment effects on OS HR with the ratio of 12-month OS milestone RMST. Size of circles indicates size of trial (ie, larger circle indicates more participants).