Table 3. Adjusted Participant-Specific Odds of Reporting More Sleep-Quality Disturbances According to Atopic Dermatitis Disease Activity and Severity^a,b.

Disease Activity and Severity	Odds Ratio (95% CI)
	Without Asthma or Allergic Rhinitis	With Asthma or Allergic Rhinitis
Never reported atopic dermatitis	1 [Reference]	1 [Reference]
Overall active atopic dermatitis	1.48 (1.33-1.66)	1.79 (1.54-2.09)
No problem	1.24 (1.04-1.48)	1.52 (1.07-2.16)
Mild	1.40 (1.27-1.54)	1.47 (1.26-1.71)
Quite bad	1.51 (1.32-1.73)	2.03 (1.66-2.48)
Very bad	1.85 (1.41-2.45)	2.28 (1.65-3.15)
Inactive atopic dermatitis	1.41 (1.28-1.55)	1.52 (1.31-1.77)

^aResults from an adjusted multivariable mixed-effects ordinal logistic regression model examining the association between atopic dermatitis and a composite measure of sleep quality (including nighttime awakenings, early morning awakenings, difficulty going to sleep, and nightmares) at 6 time points (30, 42, 57, 69, 81, and 115 months) between ages 2 and 10 years. The model adjusted for potential confounders, including child’s sex, age, race/ethnicity, and comorbid asthma or allergic rhinitis; household smoking exposure; maternal educational level, social class, and age at delivery; crowding index; and financial difficulties score as well as an interaction term between atopic dermatitis and comorbid asthma or allergic rhinitis. Model with 9112 individuals; mean (range) of 4.5 (1-6) observations per individual.

^bOverall test for interaction: P = .04.