Table 1.

Main characteristics of studies included in the present systematic review and meta-analysis

Study	Year	Country	Sex		Drugs		Duration
			Female	Male	Experimental	Control
Akhondzadeh et al22	2005	Iran	18	22	Saffron	Placebo	6 weeks
Moshiri et al24	2006	Iran	17	23	Saffron	Placebo	6 weeks
Akhondzadeh Basti et al26	2008	Iran	22	22	Saffron	Placebo	6 weeks
Mazidi et al28	2016	Iran	30	30	Saffron	Placebo	12 weeks
Noorbala et al23	2005	Iran	20	20	Saffron 30 mg	Fluoxetine 40 mg	6 weeks
Akhondzadeh Basti et al25	2007	Iran	21	19	Saffron 30 mg	Fluoxetine 20 mg	8 weeks
Shahmansouri et al27	2014	Iran	25	15	Saffron 30 mg	Fluoxetine 40 mg	6 weeks
Kashani et al29	2016	Iran	64	-	Saffron 30 mg	Fluoxetine 40 mg	6 weeks