Table 1.
Demographic, clinical-laboratorial and molecular features of pediatric T-ALL in Brazil, 2005–2017.
| Variables | Total n (%) | ETP-ALL n (%) | T-ALL n (%) | p-value |
|---|---|---|---|---|
| AGE (YEARS) | ||||
| <1 | 7 (2.5) | 2 (7.4) | 5 (20) | 0.029 |
| 1–9 | 153 (54.3) | 9 (33.3) | 144 (56.5) | |
| ≥10 | 122 (43.3) | 16 (59.3) | 106 (41.6) | |
| SEX | ||||
| Female | 72 (25.5) | 10 (37) | 62 (24.3) | 0.166 |
| Male | 210 (74.5) | 17 (63) | 193 (75.7) | |
| WBC (×109/L) | ||||
| <50 | 81 (28.7) | 13 (48.1) | 68 (26.7) | 0.042 |
| 50–100 | 53 (18.8) | 2 (7.4) | 51 (20.0) | |
| ≥100 | 148 (52.5) | 12 (44.4) | 136 (53.3) | |
| MEDIASTINAL MASS | ||||
| Yes | 114 (40.7) | 7 (25.9) | 107 (42.0) | 0.230 |
| No | 166 (58.9) | 20 (74.1) | 146 (57.3) | |
| Missing | 2 (0.7) | – | 2 (0.8) | |
| CNS INFILTRATION | ||||
| Yes | 19 (6.7) | 2 (7.4) | 17 (6.7) | 0.891 |
| No | 261 (92.6) | 25 (92.6) | 236 (92.5) | |
| Missing | 2 (0.7) | – | 2 (0.8) | |
| LYMPH NODE INFILTRATION | ||||
| Yes | 195 (69.1) | 20 (74.1) | 175 (68.6) | 0.942 |
| No | 85 (30.1) | 7 (25.9) | 78 (30.6) | |
| Missing | 2 (0.7) | – | 2 (0.8) | |
| FOLLOW UP STATUS | ||||
| Alive | 213 (75.5) | 18 (66.7) | 195 (76.5) | 0.249 |
| Dead | 69 (24.5) | 9 (33.3) | 60 (23.5) | |
| Total | 282 (100) | 27(9.5) | 255 (90.4) | |
n, number of cases; WBC, White blood cell count; CNS, central nervous system.