Table 1.
The diagnostic value of G protein-coupled estrogen receptor (GPER) for gastric cancer from six datasets.
| Study | Cut-off value | AUC | 95% CI | P-value | Sensitivity | Specificity |
|---|---|---|---|---|---|---|
| TCGA-STAD | 1.153 | 0.8133 | 0.738–0.8879 | <0.0001 | 70.97% | 70.09% |
| GSE29272 | 7.41 | 0.9562 | 0.9352–0.9772 | <0.0001 | 92.54% | 85.07% |
| Cho Gastric | 3.078 | 0.983 | 0.9596–1.006 | <0.0001 | 94.74% | 92.31% |
| Cui Gastric | 0.8941 | 0.8117 | 0.7418–0.8817 | <0.0001 | 78.48% | 75.95% |
| D’Errico Gastric | −1.1662 | 0.8566 | 0.7616–0.9517 | <0.0001 | 83.87% | 75.00% |
| Wang Gastric | −0.8643 | 0.850 | 0.6801–1.020 | 0.00213 | 93.33% | 75.00% |
TCGA-STAD – The Cancer Genome Atlas Stomach Adenocarcinoma; AUC – area under the curve; CI – confidence interval.