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Structural comparison with the closely matching prokaryotic RepA WH1. MSBI1.176 WH1 and RepA WH1 have 28% amino-acid identity. Superposition with RepA (gray) showed that these two WH1 dimers are highly similar, with an r.m.s.d. of 1.20 Å. Structural differences in extended loops were observed, noticeably the loops connecting α2 and β1 as well as β2 and β3.
