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Parameters of saturation [3H]-ryanodine binding curves in microsomes of MetS and control hearts.
| Experimental group | Bmax (pmol [3H]ryanodine/mg Pt) | Kd (nM) | Hill coefficient | N |
| Control | 0.76 ± 0.06 | 3.69 ± 0.63 | 1.4 ± 0.38 | 6 |
| MetS | 0.47 ± 0.08* | 3.41 ± 0.43 | 1.3 ± 0.23 | 5 |
Data are Mean ± SEM of indicated heart preparations for each experimental group. *P < 0.05 vs. control group.
