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. Author manuscript; available in PMC: 2019 May 7.
Published in final edited form as: Neurosci Res. 2018 Nov 16;139:3–8. doi: 10.1016/j.neures.2018.11.007

Fig. 1. Microfluidic chamber model for studying the pathways of apoptosis and axon pruning.

Fig. 1.

(Left) Illustration of microfluidic chambers in NGF maintained (top), Apoptosis (global NGF deprivation; middle), and Axon pruning (axonal NGF deprivation; bottom) conditions. (Right) Fluorescent images of neurons labeled with α-tubulin shows healthy and degenerated soma and axons in the indicated conditions.