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. 2019 Apr 13;11(7):2098–2110. doi: 10.18632/aging.101903

Table 1. Survival parameters in female WT FVB/N and K14/IGF1 mice.

WT FVB/N
(N0 = 69)
K14/mIGF1
(N0 = 46)
Difference
Maximum lifespan, days 993 770 –22.5%
Median lifespan, days 683 484 –29%
Mean lifespan, days (mean±SD) All 622±227 469±156 –25%, p<0.01
The last 10% survivors 921±36 714±35 –22%, p<0.01
Initial mortality μ0, days–1
(95% CI)
0.00014
(0.00011; 0.00016)
0.00013
(0.00009; 0.00017)
0%
Aging rate γ, days–1
(95% CI)
0.0049
(0.0046; 0.0052)
0.0077
(0.0069; 0.0084)*
+57%,
p<0.05