Table 2. Model estimates of total LPC concentration and the corresponding ratio of change between the sampling time points.

Testing between time pointsa	Model estimate of concentration change (mM)	Change ratio (95% CI)	P-valueb
Admission→3h	73→67	0.92 (0.88–0.97)	0.09
Admission→Day 1	73→69	0.94 (0.88–1.01)	0.40
Admission→Day 2	73→119	1.63 (1.51–1.76)	<0.0001
Admission→60d	73→247	3.39 (3.01–3.80)	<0.0001
3h→Day 1	67→69	1.03 (0.97–1.10)	0.68
3h→Day 2	67→119	1.77 (1.64–1.91)	<0.0001
3h→60d	67→247	3.67 (3.30–4.07)	<0.0001
Day 1→Day 2	69→119	1.73 (1.60–1.87)	<0.0001
Day 1→60d	69→247	3.60 (3.27–3.96)	<0.0001
Day 2→60d	119→247	2.08 (1.90–2.27)	<0.0001

^a The hypotheses tested were Admission-Day 1 = 0 etc.

^bValues in bold indicate significant effect.

Abbreviation: LPC, lysophosphatidylcholine.