Table 5. Model estimates of autotaxin concentration changes between the different sampling time points.

Hypothesis testing between time points	Estimate	Change Ratio (95% CI)	P-valuea
3h-Admission = 0	0.11	1.11 (1.06–1.16)	0.02
Day 1-Admission = 0	0.11	1.12 (1.05–1.21)	0.08
Day 2-Admission = 0	0.13	1.14 (1.09–1.20)	0.01
60d-Admission = 0	0.20	1.22 (1.17–1.27)	<0.0001
Day 1-3h = 0	0.01	1.01 (0.96–1.06)	0.81
Day 2-3h = 0	0.02	1.03 (0.99–1.06)	0.46
60d-3h = 0	0.09	1.10 (1.06–1.14)	0.01
Day 2-Day 1 = 0	0.01	1.01 (0.95–1.08)	0.80
60d-Day 1 = 0	0.08	1.08 (1.02–1.15)	0.17
60d-Day 2 = 0	0.07	1.07 (1.02–1.12)	0.12

^aValue in bold indicates significant effect.