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. Author manuscript; available in PMC: 2019 Dec 1.
Published in final edited form as: Curr Opin Neurobiol. 2018 Oct 16;53:198–209. doi: 10.1016/j.conb.2018.10.001

Figure 2: Molecular mechanisms regulate axon projections to specific targets.

Figure 2:

Cadherin 6 (Cdh6) RGCs (yellow) grow to Cdh6 expressing target cells in the OPN. Contactin-4 (CNTN4+) expressing RGCs (blue) act with their co-receptor amyloid precursor protein (APP) to regulate branch formation of direction-selcective ganglion cells (DSGC) in the NOT. Sema6A expressing DSGCs (green) enter the MTN by interacting with Plexin A2/A4 expressed by cells in the MTN.