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. 2019 Jan 31;151(5):645–659. doi: 10.1085/jgp.201812200

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© 2019 Robinett et al.

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Figure 2. — Transient force overshoots in slow-twitch and fast-twitch skeletal muscle fibers. (A) Representative sarcomere length trace during a slack–restretch maneuver. (Of note, the sarcomere length pattern is unresolved during the slackened period.) (B) Representative absolute force traces following a slack–restretch maneuver from a slow-twitch (black, charcoal, gray) and a fast-twitch (navy, blue, aqua) skeletal muscle fiber. (C) Force traces normalized to steady-state force before the mechanical perturbation. (D) P_TO was expressed as a fraction of steady-state force (P_o) before the slack–restretch maneuver. By two-way ANOVA, within slow-twitch (n = 5) and fast-twitch (n = 4) fiber groups, all P_TO/P_o points were significantly different from each other except at ∼25% versus ∼75% forces. *, P < 0.05, slow-twitch fibers versus fast-twitch fibers.