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Structure of the mammalian OST−translocon−ribosome complex. (A) Cryo-EM 3D map at 4.2-Å overall resolution determined in the Forster and Beckmann labs. (B) A close-up view of the translocon region using a high surface-rendering threshold as depicted in (A). (C) Docking of the yeast OST structure into the 3D map of the mammalian OST−translocon−ribosome. The identity of the red TMH is currently unknown.
