Table III –
Treatment Step Overview by Clinical Trial for Participants with Acceptable Adherence
| Control Level | ACE | ICATA | PROSE |
|---|---|---|---|
| 1 |
First visit at control level 1 Continue same controller regimen Consecutive visits at control level 1 Decrease controller regimen by 1 step. |
Decrease controller regimen by 1 step. | |
| 2 | Increase controller regimen by 1 step | ||
| 3 | Increase controller regimen by 2 steps |
No systemic corticosteroids since the last visit Increase controller regimen by 1 step** ≥1 course(s) of systemic corticosteroids since the last visit Increase controller regimen by 2 steps** |
|
| 4 | Increase controller regimen by 3 steps** | Increase controller regimen by 2 steps** | |
*
Full details in study protocols posted included as supplemental material.
**
Treatment step includes prednisone at the physician’s discretion in combination with a treatment increase