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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: J Am Soc Mass Spectrom. 2019 Mar 18;30(5):876–885. doi: 10.1007/s13361-019-02148-z

Figure 4.

Figure 4.

Coarse-grained model of an apoE tetramer. (A) An examination of the average-linkage hierarchy of all models: the dominant cluster 1 is colored in green, and cluster 2 in red. (B) The average structures of the cluster 1, cluster 2, and the tetrahedron symmetry. The C-terminal domain is colored in gray, and the N-terminal domain in green. A visual depiction of the degrees of freedom searched to give the model is shown in SI, Figure S6.. (C) The average CCSs of each cluster. Deviations compared to the averaged experimental values are in parenthesis.