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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: Ear Hear. 2020 Mar-Apr;41(2):239–253. doi: 10.1097/AUD.0000000000000536

Table 5. Calculated 90% reference intervals from the archival literature.

Reference intervals based on SEM across trials in adults have been previously published (Reavis et al. 2015). Here we show reference intervals for 3 of the studies reported by Reavis et al. (the one with the longest test-retest interval and the two with the largest samples). Results are also shown for studies not included in Reavis because they reported only the average test-retest difference. This allows comparison with 2 additional studies conducted in adults as well as 3 studies in children as young as age 3 years. Larger reference intervals are observed at high frequencies and possibly for longer baseline to follow-up times. Variability in studies of children is at the upper range of adults even though infants and toddlers were not tested.

Author Mean Age (Range) yrs Sample Size F2 kHz L1/L2 dB SPL Follow-up Interval SEM MeanShift (SD) 90% reference interval
Franklin et al 1992 30 (19–44) 12 1000–8000 65/65 4 weeks 1.17 to 2.3 2.72 to 5.35
Roede et al 1993 26 12 1000–8000 55/55 6 weeks 2.9 (2.7) 7.34
70/70 1.8 (1.8) 4.76
Beattie et al 2003 24 (19–27) 50 1000–4000 65/65 5–10 days 2.5 5.82
Ng & McPherson 2005 23 (19–35) 35 1000–6000 70/70 20 min-15 days 2.64 6.14
7000 3.04 7.07
Dreisbach et al 2006 22 (18–29) 25 2000–8000 60/45; 60/50; 70/55 4–8 weeks 2.8 (2.7) 7.24
10000–16000 5.15 (4.4) 12.39

Sockalingam et al 2007 9 (5–12) 24 2500–7000 65/55 13–15 days 0.52 (2.87) to −1.57 (4.62) 5.24 to 6.03
10000 −0.56 (5.57) 8.60
*Conrad & Dreisbach 2011 4.7 (3–6) 30 1000–6000 65/50 54 (7–277) days 0.2 (4.63) 7.82
7000–16000 −0.11 (6.02) 9.79
*Newman & Dreisbach 2012 10.7 (10–12) 37 1000–6000 65/50 51 (7–460) days −0.35 (4.88) 7.68
7000–16000 0.14 (5.31) 8.59

The 90% reference interval calculated from SEM or average difference between trials and standard deviation: +/−1.645*sqrt2*SEM OR meanshift +/− 1.645*SD

These studies represent 3 of the 10 included in Reavis et al. 2015 meta-analysis. Readers can refer to that study for data on the remaining 7 adult studies.

*

Studies were conducted using depth-compensated in-the-ear calibration.