. Author manuscript; available in PMC: 2021 Dec 1.

Published in final edited form as: J Nucl Cardiol. 2018 Nov 7;27(6):1982–1998. doi: 10.1007/s12350-018-01471-4

Table 4.

Flow and spillover statistical analysis

		Test of mean difference		Test of variance
		Automated vs manual correction		Uncorrected vs automated	Uncorrected vs manual	Automated vs manual
Quantity	Region	P	Effect size	P	P	P
Stress MBF	Global	.35	0.00	<.0001^*	<.0001^*	.33
	LAD	.13	−0.03	<.0001^*	.047^*	1.00
	LCX	.072	0.01	1.00	1.00	1.00
	RCA	.0056^*	0.02	<.0001^*	<.0001^*	1.00
Rest MBF	Global	.00036^*	0.01	1.00	1.00	1.00
	LAD	.035^*	0.01	.00046^*	.51	1.00
	LCX	<.0001^*	0.02	.54	.48	1.00
	RCA	.086	0.01	.29	.00094^*	1.00
MFR	Global	.054	−0.02	.51	1.00	.54
	LAD	.0011^*	−0.04	1.00	1.00	1.00
	LCX	.044^*	−0.03	1.00	1.00	1.00
	RCA	.30	0.01	<.0001^*	<.0001^*	1.00
Spillover	Global	<.0001^*	−0.02	<.0001^*	<.0001^*	<.0001^*
	LAD	<.0001^*	−0.02	<.0001^*	.40	.00010^*
	LCX	<.0001^*	−0.01	<.0001^*	.04^*	<.0001^*
	RCA	<.0001^*	−0.01	<.0001^*	<.0001^*	.00033^*

MBF, myocardial blood flow is in mL.min⁻¹.g⁻¹; and MFR, myocardial flow reserve is unitless. Spillover includes stress and rest. Effect size is the difference of means.

indicates statistical significance of P-values < .05.

^†

indicates substantive significance of a large effect size using an alternate Cohen’s d > 0.8 which is unitless