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. 2019 May 1;11:3887–3898. doi: 10.2147/CMAR.S199912

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© 2019 Bu et al.

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Dsf suppressed TGFβ1-induced migration and invasion in OSCC cells.

Notes: (A, E) Transwell-based migration assays were performed to check the effect of Dsf on cell migration of Smad4-mutated CAL27 and Smad4 wild-type SCC25 cells exposed to TGFβ₁ (10 ng/mL). (B, F) Quantification of cell migration. (C, G) Transwell-based invasion assays were performed to check the effect of Dsf on cell invasion of Smad4-mutated CAL27 and Smad4 wild-type SCC25 cells exposed to TGFβ₁ (10 ng/mL). (D, H) Quantification of cell invasion. Values represent mean ± SEM. *P<0.05; **P<0.01; ***P<0.001; bar 300 μm.

Abbreviation: Dsf, disulfiram; OSCC, oral squamous cell carcinoma.