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. 2019 May 1;10:447. doi: 10.3389/fneur.2019.00447

Table 1.

Values are means ± S.E.M. Baseline values reported are averaged from two measurements recorded 30 min apart.

Time point Control Asphyxia (+) Asphyxia (−) Asphyxia + SOD Asphyxia + C3 Asphyxia + Oxypurinol (5 mg/kg) Asphyxia + Oxypurinol (50 mg/kg)
MEAN ARTERIAL BLOOD PRESSURE (mm Hg)
Baseline 56 ± 1 57 ± 2 59 ± 1 55 ± 1 54 ± 1 55 ± 2 56 ± 1
1 h 55 ± 1 54 ± 2 58 ± 1 53 ± 1 51 ± 1 54 ± 2 55 ± 1
2 h 56 ± 1 52 ± 2 55 ± 1# 53 ± 0 52 ± 2 51 ± 1 54 ± 1
BLOOD GLUCOSE (mg/dL)
Baseline 88 ± 7 104 ± 6 103 ± 5 95 ± 5 126 ± 3* 111 ± 22 91 ± 4
1 h 92 ± 7 120 ± 5* 117 ± 10 106 ± 8 135 ± 8* 112 ± 12 109 ± 10
2 h 93 ± 7 122 ± 6 107 ± 10 93 ± 10 124 ± 15 88 ± 10 89 ± 8
ARTERIAL pH
Baseline 7.38 ± 0.01 7.36 ± 0.01 7.38 ± 0.01 7.34 ± 0.02 7.34 ± 0.02 7.41 ± 0.02 7.37 ± 0.02
1 h 7.36 ± 0.01 7.31 ± 0.02 7.32 ± 0.02 7.29 ± 0.02 7.29 ± 0.01 7.35 ± 0.02 7.33 ± 0.02
2 h 7.35 ± 0.01 7.35 ± 0.02 7.34 ± 0.02 7.33 ± 0.02 7.34 ± 0.02 7.40 ± 0.01 7.36 ± 0.01
ARTERIAL PARTIAL PRESSURE OF CO2 (mm Hg)
Baseline 40 ± 1 38 ± 1 38 ± 1 38 ± 1 43 ± 1 37 ± 1 37 ± 2
1 h 41 ± 1 38 ± 2 40 ± 1 39 ± 1 41 ± 3 37 ± 2 40 ± 2
2 h 40 ± 1 35 ± 1 39 ± 1 39 ± 2 41 ± 2 36 ± 2 38 ± 3
ARTERIAL PARTIAL PRESSURE OF O2 (mm Hg)
Baseline 94 ± 3 98 ± 3 95 ± 2 94 ± 3 88 ± 2 96 ± 3 91 ± 2
1 h 96 ± 2 101 ± 3 105 ± 4 103 ± 4 98 ± 4 93 ± 3 102 ± 4
2 h 92 ± 2 105 ± 4 100 ± 2 94 ± 2 112 ± 11* 94 ± 3 99 ± 4

(+), with aCSF superfusion across the cranial window; (−), without aCSF superfusion across the cranial window.

*

p < 0.05 vs. control at the same time point;

#

p < 0.05 vs. baseline mean arterial blood pressure value for asphyxia without aCSF superfusion.