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. 2019 May 1;10:853. doi: 10.3389/fimmu.2019.00853

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Copyright © 2019 Valoti, Alberti, Iatropoulos, Piras, Mele, Breno, Cremaschi, Bresin, Donadelli, Alizzi, Amoroso, Benigni, Remuzzi and Noris.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Distribution of age at disease onset in aHUS patients analyzed for anti-FHs. (A) Patients with anti-FHs (n = 30); (B) Patients without anti-FHs (n = 275), and (C) Patients without anti-FHs and carrying LPVs in complement genes (n = 99).