Table 4.
Anti-inflammatory activity of 80% methanolic extract and solvent fractions of Cucumis ficifolius on carrageenan-induced paw edema
| Group | Percent inflammation ± SEM (% inflammation inhibition) | ||||
|---|---|---|---|---|---|
| 1 hr | 2 hrs | 3 hrs | 4 hrs | ||
| NC | 54±0.043 | 67±0.04 | 73±0.04956 | 65±0.02 | |
| CM200 | 48±0.06 (22) | 57±0.061 (24)* | 58±0.06 (30)** | 44±0.04 (40)*** | |
| CM400 | 43±0.08 (34)** | 46±0.08 (44)*** | 47±0.086 (48)*** | 35±0.034 (56)*** | |
| CM800 | 36±0.035 (44)** | 30±0.032 (51)*** | 35±0.031 (60)*** | 23±0.039 (71)*** | |
| AQ100 | 49±0.089 (24) ** | 54±0.08 (33) a*** | 56±0.08 (37) a*** | 46±0.064 (41) a*** | |
| AQ200 | 45±0.045 (37) *** | 46±0.056 (50) *** | 49±0.037 (51) *** | 39±0.03 (56) *** | |
| B100 | 48±0.059 (34) *** | 50±0.052 (44) *** | 52±0.050 (48) *** | 39±0.04 (53) *** | |
| B200 | 44±0.063 (42) *** | 48±0.0476 (48) *** | 46±0.0589 (56) *** | 28±0.033 (69) *** | |
| ASA200 | 50±0.06 (29) *** | 57±0.061 (35) *** | 58±0.055 (40) *** | 33±0.063 (62) *** | |
Note: **p<0.01, ***p<0.001.
Abbreviations: AQ100, aqueous fraction 100 mg/kg; AQ200, aqueous fraction 200mg/kg; ASA200, acetylsalicylic acid 200mg/kg; B100, butanol fraction 100mg/kg; B200, butanol 200mg/kg; CM200, crude extract 200mg/kg; CM 400, crude extract 400mg/kg; CM800, crude extract 800mg/kg; NC, negative control; SEM, standard error of the mean.