Fig. 2. Guideline for patients with age ≤70 years. Patients with good performance are recommended to be treated by concurrent chemoradiotherapy with temozolomide followed by adjuvant temozolomide chemotherapy (Stupp's protocol) or standard brain radiotherapy alone. However, those with poor performance are recommended to be treated by hypofractionated brain radiotherapy (preferred)±concurrent or adjuvant temozolomide, temozolomide alone (Level III), or supportive treatment. KSNO, Korean Society for Neuro-Oncology; KPS, Karnofsky Performance Scale; ECOG, Eastern Cooperative Oncology Group; MRI, magnetic resonance image.
