Table 3. The gene pair TP53/ATRX had 191 significantly co-occurrent alterations; the pair VWF/TP53 had 26 significantly co-occurrent alterations; the pair VWF/ATRX had 23 significantly co-occurrent alterations.
| Gene A | Gene B | Neither | A Not B | B Not A | Both | Log odds ratio | p-value | Adjusted p-value | Tendency |
|---|---|---|---|---|---|---|---|---|---|
| TP53 | ATRX | 243 | 58 | 15 | 191 | >3 | <0.001 | <0.001 | Co-occurrence |
| VWF | TP53 | 255 | 3 | 223 | 26 | 2.294 | <0.001 | <0.001 | Co-occurrence |
| VWF | ATRX | 295 | 6 | 183 | 23 | 1.821 | <0.001 | <0.001 | Co-occurrence |
p value was Bonferroni adjusted. VWF, von Willebrand factor