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. 2019 May 1;9:134. doi: 10.3389/fcimb.2019.00134

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Copyright © 2019 Loeuillet, Mondon, Kamche, Curri, Boutonnat, Cavaillès and Cesbron-Delauw.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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GUY008-ABE induced heart and lungs tissues reorganization. Rats were intraperitoneally infected with 10⁷ tachyzoites of type II Prugniaud or GUY008-ABE strains and organs histological analysis performed at day14 post-infection with an haematoxilin and eosin staining. (A–H) Represent the un-infected F344 rat, (I–P) the Prugniaud-infected rat and (Q–X) the GUY008-ABE-infected rat. (A,B,I,J,Q,R) Correspond to heart histological images, (C,D,K,L,S,T) to lungs images, (E,F,M,N,U,V) to liver images and (G,H,O,P,W,X) to brain images. Magnifications were x4 for panels (A,C,E,G,I,K,M,O,Q,S,U,W) and x40 for (B,D,F,H,I,L,N,P,R,T,V,X). Arrows on (N) indicate the portal vein sinus; on (P,R,T), parasite foci; on (V), histiocytic infiltration and on (X) parasites inside macrophages.