Table 2.
The percentage of surviving mice colonized with F. tularensis at the end of the study.
| Time of treatment initiation post-challenge (hrs) | Treatment | Proportion of survivors colonized (%) |
|---|---|---|
| 24 | Finafloxacin | 20 |
| Ciprofloxacin | 40 | |
| 48 | Finafloxacin | 10 |
| Ciprofloxacin | 40 | |
| 72 | Finafloxacin | 78 |
| Ciprofloxacin | 50 | |
| 96 | Finafloxacin | 100 |
| Ciprofloxacin | 100 |
Surviving animals were culled at day 35, the organs harvested and the presence of F. tularensis determined.