Table 1.
Category | Term | Count | % | p | Benjamini | Fold enrichment |
---|---|---|---|---|---|---|
Gene enrichment analysis of downregulated genes after inactivity | ||||||
UP_KEYWORDS | Mitochondrion | 49 | 20.94 | 1.5E-16 | 3.14E-14 | 4.00 |
UP_KEYWORDS | Muscle protein | 8 | 3.42 | 5E-06 | 0.00036 | 11.74 |
KEGG_PATHWAY | hsa00190:Oxidative phosphorylation | 8 | 3.42 | 0.00303 | 0.03573 | 4.12 |
KEGG_PATHWAY | hsa04920:Adipocytokine signaling pathway | 7 | 2.99 | 0.00049 | 0.01087 | 6.84 |
GOTERM_CC_DIRECT | GO:0005753∼mitochondrial proton-transporting ATPsynthase complex | 4 | 1.71 | 0.00200 | 0.05541 | 15.62 |
Gene enrichment analysis of upregulated genes after inactivity | ||||||
UP_KEYWORDS | Muscle protein | 6 | 1.78 | 0.00296 | 0.08000 | 6.10 |
Gene enrichment analysis of downregulated genes after exercise | ||||||
COG_ONTOLOGY | Energy production and conversion | 4 | 3.15 | 0.00086 | 0.00257 | 18.33 |
Gene enrichment analysis of upregulated genes after exercise | ||||||
UP_KEYWORDS | Mitochondrion | 41 | 11.39 | 7.3E-06 | 0.00031 | 2.15 |
Category, original database/resource where the term orient; term, enriched terms associated with the gene list; count, genes involved in term; %, percentage of genes involved/total genes; p, modified fisher exact p-value, EASE Score; Benjamini, statistical correction; fold enrichment, down (up) regulated genes in a specific category/term over total down (up) regulated genes (%)/number of genes in that category/term over total number of genes (%). Lists of the top DEG in Supplementary Tables S1, S2. For DEG analysis, see Supplementary Table legends.