Table 3.

Mitochondria-related genes negatively correlated with age in vastus lateralis. GSE47881 dataset.

Category	Term	Count	%	p	Benjamini	Fold enrichment
Gene enrichment analysis of genes negatively correlated with age (Spearman correlation analysis)
GOTERM_CC_DIRECT	GO:0005743∼mitochondrial inner membrane	32	7.27	5.5E-09	1.99E-06	3.42
UP_KEYWORDS	Mitochondrion	50	11.36	1.97E-07	2.19E-05	2.24
UP_KEYWORDS	Transit peptide	26	5.91	0.0000819	0.00679	2.43

Rule of thumb for interpreting the size of a correlation coefficient was used. Genes with a significant negative strong correlation were selected (correlation coefficient -0.6 ≤ r ≤-0.8), Benjamini–Hochberg corrected p-values < 0.05. Category, original database/resource where the term orient; term, enriched terms associated with the gene list; count, genes involved in term; %, percentage of genes involved/total genes; p, modified Fisher Exact p-value, EASE Score; Benjamini, statistical correction; fold enrichment, down (up) regulated genes in a specific category class over total down (up) regulated genes (%)/number of genes in that category class over total number of genes (%). Lists of the top negatively correlated genes in Supplementary Table S5.