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. Author manuscript; available in PMC: 2019 Dec 12.
Published in final edited form as: Chem Rev. 2018 Oct 31;118(23):11298–11323. doi: 10.1021/acs.chemrev.8b00513

Figure 9.

Figure 9.

Mechanistic interpretation of how macromolecular crowding enhances DNA translocation by associative and dissociative pathways (see text). Most of the effects can be explained by a macromolecular cage that surrounds the protein–DNA complex.