Table 1.
Clinical, biochemical, and seminal characteristics of controls and obese patients
| Controls (n = 10) | Obese patients (n = 20) | P | |
|---|---|---|---|
| Age (years) | 34 ± 5 | 40 ± 8 | 0.055 |
| Weight (kg) | 77 ± 8 | 146 ± 27 | 0.000 |
| Body mass index (kg/m2) | 24 ± 2 | 48 ± 9 | 0.000 |
| Excess body weight (kg) | 3 ± 6 | 70 ± 26 | 0.000 |
| Total cholesterol (nmol/L) | 177 ± 33 | 192 ± 33 | 0.381 |
| Low-density lipoprotein cholesterol (nmol/L) | 2.90 ± 0.78 | 3.57 ± 0.78 | 0.038 |
| High-density lipoprotein cholesterol (nmol/L) | 1.11 ± 0.18 | 0.96 ± 0.18 | 0.063 |
| Triglycerides (nmol/L) | 1.23 ± 0.50 | 1.98 ± 0.79 | 0.025 |
| Total testosterone (nmol/L) | 21.6 ± 6.0 | 12.9 ± 5.8 | 0.001 |
| Sex hormone–binding globulin (nmol/L) | 4.1 ± 1.3 | 2.9 ± 0.8 | 0.011 |
| Free testosterone (pmol/L) | 439 ± 103 | 302 ± 137 | 0.008 |
| Estradiol (pmol/L) | 84 ± 15 | 147 ± 48 | 0.008 |
| Follicle-stimulating hormone (U/L) | 2.6 ± 1 | 3.6 ± 1.9 | 0.199 |
| Luteinizing hormone (U/l) | 4.1 ± 0.6 | 3.5 ± 1.3 | 0.123 |
| Fasting glucose (mmol/L) | 5.1 ± 0.7 | 6.8 ± 3.6 | 0.328 |
| Fasting insulin (pmol/L) | 49 ± 28 | 181 ± 83 | 0.000 |
| Semen volume (mL) | 3.7 ± 1.9 | 2.8 ± 1.3 | 0.281 |
| Sperm concentration (106/mL) | 72.5 ± 18.3 | 40.9 ± 34.9 | 0.038 |
| Total motility (%) | 58 ± 4 | 37 ± 18 | 0.001 |
| Progressive motility (%) | 43 ± 3 | 18 ± 7 | 0.001 |
| Immobile (%) | 43 ± 4 | 64 ± 18 | 0.001 |
*Data are shown as means ± SD