Table 1.
Main flaviviruses associated with CNS infections in children in Brazil
| Virus | No. of cases | Mode of diagnosis | CNS manifestation | State | Reference |
|---|---|---|---|---|---|
| DENV | 1 | Serology | Encephalitis | Rio de Janeiro | Soares, 2006 [20] |
| 1 | Serology | Acute disseminated encephalomyelitis | Rondônia | Miranda de Sousa, 2006 [22] | |
| 2 | PCR | Encephalitis | Espírito Santo | Domingues, 2008 [21] | |
| 3 | Serology | Meningitis | Ceará | Araújo, 2012 [19] | |
| 7 | PCR and serology | Meningoencephalitis | Minas Gerais | Marinho, 2017 [17] | |
| 5 | PCR and serology | Meningitis | Minas Gerais | De Oliveira, 2017 [18] | |
| 5 | PCR and serology | Encephalitis and meningitis | Amazonas | Bastos, 2018 [23] | |
| SLEV | 3 | PCR | Meningoencephalitis | São Paulo | Mondini, 2007 [32] |
| ZIKV | 1 | PCR | Encephalitis | — | Vieira, 2018 [26] |
CNS, central nervous system; DENV, Dengue virus; SLEV, St Louis encephalitis virus; ZIKV, Zika virus.